(An asterisk indicates that a non-refundable laboratory fee is required.)
109 Plagues, Outbreaks, and Biological Warfare. One unit. Three hours of lecture weekly. This course is designed for non-science majors and meets the science distribution requirement. The course focuses on historical epidemics with emphasis on how scientists discovered, treated, and halted the spread of these illnesses and how the diseases shaped societies. Present-day epidemics are examined and attention is given to future epidemic threats. Organisms used in biological warfare are described. No prerequisites. Offered as needed.
200 Microbiology. One unit. Three hours of lecture and two hours of laboratory weekly. This course is a study of microorganisms with special emphasis on those that affect the human body. The study of pathogenic organisms is introduced, including the more common tests for infectious diseases and the specific immunities by which the body is protected. Primarily for science and health science majors. Not recommended as a sole course in microbiology to meet distribution requirements. Offered fall and spring semesters.*
216 General Pathology. One unit. Three hours of lecture and two hours of laboratory weekly. A course in the principles, techniques, and clinical significance of standard clinical laboratory procedures in hematology, clinical biochemical analyses, and immunohematology. Cross-listed as Biology 216. Prerequisites: Microbiology 200. Prerequisite or corequisite: Chemistry 112. Offered spring semester.*
219 Gene Expression and Development. One unit. Three hours of lecture and two hours of laboratory weekly. A course designed to familiarize students with fundamental biological principles emphasizing DNA replication, transcription, translation, control of gene expression, and genomics. Gametogenesis, fertilization, early embryonic development, sex, and reproduction are considered in light of the molecular mechanisms involved. Laboratory experiments give students hands-on experience with various aspects of molecular biology and development. (Cross-listed as Biology 219.) This course is not recommended for non-science majors. Prerequisite: Microbiology 200. Offered fall and spring semesters.*
221 Biostatistics and Experimental Design. One unit. Three hours of lecture and one hour of recitation weekly. This course provides an introduction to hypothesis testing, experimental design, and the statistical treatment of biological information. Fundamental aspects of data analysis are presented, including parametric and nonparametric testing procedures commonly used in biological research. Cross-listed as Biology 221. Prerequisites: Completion of any mathematics deficiencies; one unit of biology or one unit of microbiology. Offered fall and spring semesters.
291 Special Topics in Microbiology. One unit. Weekly lecture(s). Discussion and analysis of problems in microbiology which are not covered in regular course work. The specific content of the course will remain flexible in response to student and departmental interest. Special topics may be taken more than once with differing subject matters. Offered periodically; consult department chair.
314 Clinical Microbiology. One unit. Three hours of lecture weekly. Standard methods for the bacteriological examinations of blood, urine, sputum, spinal fluid, and other body secretions and excretions. Prerequisite: Microbiology 200. Offered spring semester of odd-numbered years.*
397 G, P, or N Internship in Microbiology. One or zero units. Research or teaching experience for at least 105 hours in a research, clinical, industrial, or teaching setting where there is supervised, hands-on involvement in daily activities. The student will maintain a log describing day-to-day activities and the times and hours worked. A final paper in which the student evaluates the work experience is required. Other possible requirements will be determined by the faculty member overseeing the student’s progress. The student’s on-site supervisor will complete a written evaluation of the student’s performance and submit it to the faculty supervisor. Students registered for this course as MI 397G will receive a letter grade; those registered as MI 397P will be taking the course on a pass/fail basis; those registered as MI 397N will be taking the course for no credit (registration fee required). This course cannot be used to meet requirements for the senior Reflective Tutorial in Microbiology (MI 400) nor does it count towards completion of the requirements for the microbiology major. Interested students should contact the Center for Academic and Career Development. Prerequisites: MI 200 and permission of department chair. Offered as needed.
400E Experiential Component of Reflective Tutorial in Microbiology. Zero units. This zero-unit course is the experiential component of the senior learning community and is linked to Reflective Tutorial in Microbiology (Microbiology 400). It includes at least 120 hours of research or internship. The research or internship experience must be completed prior to Microbiology 400, as determined by the chair of the student's senior review committee. This experiential component serves as the basis for the review paper or research papaer completed in Microbiology 400. Permission of Departmental Senior Reflective Tutorial Coordinator required. Offered fall, spring, and summer.
400 Reflective Tutorial in Microbiology. One unit. This course is linked to a completed research or internhip experience which includes at least 120 hours of research or internship. The course must be taken during the senior year, as a part of the senior learning community, by all microbiology majors. In this course the student who has completed an internship prepares a review paper on a topic related to the internship experience, while the student who has completed independent research analyzes his/her own data and completes an original research paper. Writing will follow standard scientific journal formats. Each student is required to succesfully defend his/her paper before a senior review committee. All students are also expectd to present their findings publicly in oral or poster form using venues that are deemed appropriate by the instructor. Prerequisites: Completion of research or internship experience (Microbiology 400E), as determined by the chair of the student's senior review committee, is required prior to the beginning of this course. Offered fall and spring semesters.
491 Capstone Course: Recent Advances in Microbiology. One unit. Three hours of lecture weekly. This course addresses recent advances in research and concepts within the following microbiology disciplines: molecular cell biology, microbial physiology, microbial genetics, environmental microbiology, clinical microbiology, immunology, virology, and applied microbiology. Specifc lectures are provided by faculty. Each student actively particpates by preparing and presenting lectures in all fields. This course is part of the senior learning community in microbiology and is normally taken during the senior year. Prerequisites: Microbiology 200, 219, 221, 314, 512, 521, 522, and 525. Offered spring semester.
493 Undergraduate Research I. One unit. A minimum of eight hours per week of supervised research on a selected topic culminating in a research paper using the format of any preferred scientific journal in biology. A minimum of 10 references to the selected topic is required. Students taking this course for credit may not use the research experience to meet Microbiology 400E requirements for the senior learning community. Permission of the instructor is required. Prerequisites: Four units of microbiology including Microbiology 221. Students not majoring in microbiology shoudl seek permission of chairs of his/her own department and of the Department of Biological Sciences. Offered fall and spring semesters.*
494 Undergraduate Research II. One unit. A minimum of eight hours per week of supervised research on the same selected topic as in Microbiology 493. A rare student has the possibility of completing the research started as Microbiology 493 for publication consideration. The course culminates in a research paper using the format of the scientific journal selected for consideration for publication. An additional 10 references tot he selected topic are required. Students taking this course for credit may not use the research experience to meet Microbiology 400E requirements for the senior learning community. Permission of the instructor is required. Prerequisite: Microbiology 493. Offered as needed.*
495 Molecular Cell Biology. One unit. Three hours of lecture and three hours of laboratory weekly. An examination of current knowledge concerning eukaryotic cell structures and functions. Topics covered include cell organelles, membranes and membrane trafficking, the nucleus and nuclear membrane, cell signaling and communication. A molecular perspective is emphasized throughout the course. Cross-listed as Biology 495. Senior status required. Prerequisites: BI 213, 219 and permission of the instructor. Offered spring semester.*
497 G, P, or N Internship in Microbiology. Two or zero units. Research, clinical, industrial, or teaching experience for at least 210 hours at a facility where there is supervised, hands-on involvement in daily activities. The student will maintain a log describing day-to-day activities and the times and hours worked. A final paper in which the student evaluates the work experience is required. Other possible requirements will be determined by the faculty member overseeing the student’s progress. The student’s on-site supervisor will complete a written evaluation of the student’s performance and submit it to the faculty supervisor. Students registered for this course as MI 497G will receive a letter grade; those registered as MI 497P will be taking the course on a pass/fail basis; those registered as MI 497N will be taking the course for no credit (registration fee required). This course cannot be used to meet requirements for the senior Reflective Tutorial in Microbiology (MI 400) nor does it count towards completion of the requirements for the microbiology major. Interested students should contact the Center for Academic and Career Development. Prerequisites: MI 200 and permission of department chair. Offered as needed.
503 Epidemiology. One undergraduate unit or three graduate credits. Three hours of lecture weekly. An intensive course in the principles and methods of epidemiology with special reference to the determination of community needs. Prerequisites: Microbiology 200 and a course in statistical methods. Offered spring semester of even-numbered years.
512 Applied, Food, and Industrial Microbiology. One undergradaute unit or four graduate credits. Three hours of lecture and two hours of laboratory weekly. This course includes bacteriological studies of water, sewage, milk, and food. In this course emphasis is also placed on microbiological assays, toxicology studies, and purposes and procedures involved in the standardization of antibiotics, germicides, preservatives, and disinfectants. Prerequisites: Microbiology 200, 221; Chemistry 112. Offered spring semester of odd-numbered years.*
513 Pathogenic Fungi. One undergraduate unit or four graduate credits. Three hours of lecture and two hours of laboratory weekly. A study of the morphology, taxonomy, and phylogeny of pathogenic fungi and the pathology of mycological diseases in animals, including humans. The isolation, identification, and study of fungi for purposes of classifaction, physiology, ecology, and genetics. Prerequisite: Microbiology 200. Offered fall semester of odd-numbered years.*
517 Electron Microscopy. 1 unit or 4 credits. Six hours of combined lecture and laboratory weekly. The principles and use of the transmission and scanning electron microscopes are covered. Students learn the basic techniques of electron microscopic tissue processing and microphotography. Each student must prepare a final technical report including examples of their own microphotographs. Prerequisites: MI 200; CH 111, 112 and permission of instructor. Not open to students completing MI 615. Offered as required.*
521 Immunology and Serology. One undergraduate unit or four graduate credits. Three hours of lecture and two hours of laboratory weekly. The principles of immunology including the immune response, immunoglobulin production theories, standard serological methods, and serodiagnostic procedures. Prerequisites: Microbiology 200; Chemistry 211, 211L; and eight additional credits in biology or microbiology. The course is closed to graduate students who have taken an upper level undergraduate or graduate immunology course. Offered fall semester of even-numbered years.*
522 Microbial Genetics. One undergraduate unit or four graduate credits. Three hours of lecture and two hours of laboratory weekly. The genetics of bacteria, fungi, bacteriophages, and other viruses. Particular emphasis is placed on the experimental use of microorganisms in the study of molecular events in genetics, including DNA replication, macromolecular synthesis and regulation, mutation, recombination, and DNA repair. Prerequisites: Microbiology 200, 219, 221; Chemistry 211, 211L. Offered spring semester of odd-numbered years.*
523 Microbial Ecology. One undergraduate unit or four graduate credits. Three hours of lecture and two hours of laboratory weekly. This course is an introduction to the ecology of microorganisms. Involvement of microorganisms in nutrient cycles is emphasized. Applications in the areas of deterioration of products and disposal of wastes are addressed. Prerequisites: Chemistry 211, 211L; and eight credits of laboratory courses in micrioloby. Offered as required.*
524 Molecular Genetics. One undergraduate unit or four graduate credits. Three hours of lecture and two hours of laboratory weekly. A course on the application of molecular knowledge to the problems of genetic engineering. A comparison between the genetic systems of prokaryotes and eukaryotes and their roles in molecular genetic techniques used in the fields of molecular biology and microbiology are explored. The development of current concepts and methods in molecular genetics as they apply to research, agriculture, industries, pharmaceutical companies and medicine are studied. The laboratory explores the current techniques used in recombinant DNA technology as they relate to the course material. Cross-listed as Biology 524. Prerequisite: Microbiology 522. Offered as required.*
525 Microbial Physiology. One undergraduate unit or four graduate credits. Three hours of lecture and two hours of laboratory weekly. Students study the structure, function, and assembly of microbial cells and analyze products of their metabolism. Prerequisites: Microbiology 200; Chemistry 211, 211L. Offered fall semester of odd-numbered years.*
591 Special Topics in Microbiology. One undergraduate unit or one-to-four graduate credits. Weekly lecture(s). Discussion and analysis of problems in microbiology that are not covered in regular course work. The specific content of the course remains flexible in response to student and departmental interest. Special topics may be taken more than once with differing subject matter. Offered periodically; consult the director of the microbiology graduate program.
593 Independent Study. Supervised independent research projects developed by the student, with faculty advisement. Restricted to advanced majors. Offered fall and spring semesters.
611 Medical and Public Health Microbiology. Four graduate credits. Two hours of lecture and two hours of laboratory weekly. Medical and public health microbiology including immunology. Standard techniques for the microbiological examination of clinical specimens, including common tests for infectious disease organisms. Prerequisites: Microbiology 200 or equivalent, or permission of the department chair. Offered fall semester. Course may be waived by department action for those students having extensive clinical microbiology background. A formal request and supporting documentation should be sent to the director of the microbiology graduate program.*
612 Pathology. Three graduate credits. Two hours, 40 minutes of lecture weekly. General systemic pathology, including the study of the reaction to injury and the structural and physiological changes in diseases. The pathology of diseases due to bacteria, viruses, rickettsiae, and parasites is emphasized. Prerequisites: Microbiology 611. Offered fall semester of odd-numbered years.
615 Electron Microscopy. Four graduate credits. Six hours of combined lecture and laboratory weekly. The principles and use of the transmission and scanning electron microscopes are covered. Students learn the basic techniques of electron microscopic tissue processing and microphotography. An independent, short project must be performed and a research format paper with self prepared illustration is required. Prerequisite: Graduate standing in microbiology and permission of instructor. Students other than those in the microbiology masters program should seek permission of the department chair. Not open to students completing BI/MI 517. Offered as needed.*
618 Parasitology. Three graduate credits. Two hours, 40 minutes of lecture weekly. This course involves the study of the morphology, taxonomy, and phylogeny of human parasites. Prerequisite: Microbiology 611. Offered spring semester of odd-numbered years.
619 Virology. Three graduate credits. Two hours, 40 minutes of lecture weekly. A basic course in structure, replication, and effects of virus infection. Special attention is given to medically important viruses. The methods of identification and growth of viral agents are considered. Prerequisite: Microbiology 611. Offered as needed.
621 Topics in Immunobiology and Immunochemistry. Three graduate credits. Two hours, 40 minutes of lecture weekly. This is an advanced course in current immunology. Topics include structure and function of immunoglobulins, T-cells and B-cells, characteristics of synthetic and natural antigens, and the cellular aspects and kinetics of antibody formation. Hybridoma research will also be explored. Prerequisites: Microbiology 521, 611, or equivalent. Offered fall semester of even-numbered years.
623 Microbial Pathogenesis. Three graduate credits. Two hours, 40 minutes of lecture weekly. This course deals with the complex and multi-faceted nature of microbial disease. Emphasis is placed on the interaction between the host and the microorganisms. Approaches and concepts from cell biology, microbiology, and immunology are utilized in teaching the course. Prerequisite: Microbiology 525. Offered spring semester of odd-numbered years.
626 Advanced Microbial Physiology. Four graduate credits. Two hours of lecture and two hours of laboratory weekly. Microbial nutrition, kinetics of growth, and biosynthesis of major cell constituents and their transport and assemblage. Enzymes of terminal oxidation, synthesis, and metabolism of cellular intermediates are studied. Prerequisite: Microbiology 525 or equivalent. Offered spring semester of even-numbered years.*
628 Microbiology of Antimicrobial Agents. Three credits. This course examines the history, uses, and roles of antibacterial, antifungal, antiprotozoal, antihelminthic, and antiviral agents in combating infectious disease. It explores the mechanisms used by microorganisms to resist these compounds, standard methods of susceptibility testing, and the ways in which resistance determinants evolve and spread. Material is presented using a combination lecture/discussion group format, where students directly apply what they learn in class to interpreting current research articles drawn from the biomedical and scientific literature. Prerequisites: Microbiology 611 or equivalent. Offered spring semeter of even-numbered years.
691 Special Topics in Microbiology. One-to-four graduate credits. Weekly lectures. Discussion and analysis of problems in microbiology that are not covered in regular course work. The specific content of the course remains flexible in response to student and departmental interest. Special topics may be taken more than once with differing subject matter. Offered periodically; consult with the director of the microbiology graduate program.
693 Independent Study in Microbiology. One-to-four graduate credits. A course designed for advanced graduate-level inquiry. Qualified students may carry out independently arranged study of their own, chosen after advisement by sponsoring department facutly. The project may be experimental, descriptive, or analytical. Prerequisite: Permission of the director of the microbiology graduate program and an advisor. Offered fall and spring semesters.
797, 798, 799 Research. Six graduate credits. Research on an experimental problem in a specialty of microbiology in which the student chooses to write a thesis required for the master's degree. Prerequisite: Permission of the director of the microbiology graduate program. Offered fall and spring semesters.*
